Rifampicin Resistance in Tuberculosis Outbreak, London, England
نویسندگان
چکیده
Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.
منابع مشابه
Increasing antituberculosis drug resistance in the United Kingdom: analysis of National Surveillance Data.
OBJECTIVE To identify recent trends in, and factors associated with, resistance to antituberculosis drugs in England, Wales, and Northern Ireland. DESIGN Cohort of tuberculosis cases reported to the enhanced tuberculosis surveillance system matched to data on drug susceptibility and national strain typing data. SETTING England, Wales, and Northern Ireland 1998-2005. MAIN OUTCOME MEASURES ...
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